According to a recent report from the American Physicists Organization Network, a recent joint study by the Indiana University and Purdue University Indianapolis (IUPUI) and Umea University (Sweden) showed that there is a cell for repair The method of self-DNA break (called break-induced replication) is 2800 times higher than the genetic variation produced by normal synthetic DNA.
To accurately transmit genetic information, DNA must be copied accurately. However, DNA replication errors are common. Cells have developed several mechanisms to repair these errors, and mutation is one of them. In terms of evolutionary adaptability, this is advantageous, but for individual life, mutations are considered harmful and may develop cancer cells.
The researchers used yeast to study the level of gene mutations associated with break-induced replication, and found that the possibility of genetic variation during this process was not related to the site of DNA repair. Anna Mokova, an associate professor of biology at the IUPUI School of Science who led the study, said: "In the case of break-induced replication, it is not a 'bandage' to repair chromosome breaks, so that the fragments will invade other chromosomes and begin to replicate , It is likely that the wrong protein was added at the wrong time and in the wrong place. "
For what causes the error rate of fracture-induced replication to be much higher than normal replication, Mokova said that at least 4 changes in the replication system may cause a synergistic storm, resulting in high induction during the repair process Variations, such as the nucleotides that make up DNA, are concentrated in large amounts. "We believe that the real culprit has not been found."
The researchers also pointed out that gene mutations caused by break-induced replication do not occur slowly, but instead suddenly occur, which may lead to cancer. Mokova said the joint team will further study why rupture-induced replication will bring such high mutations to cell repair, and eventually find a way to prevent these mutations from causing cancer.
Hair Curlers And Curling Tongs
The 2-in-1 Hair Straightener And Hair Curler is an ideal, multifunctional brush iron that realizes a variety of hairstyles such as naturally straight hair, volumised top and curls in different sizes - as you like according to the occasion. The hair-catching clip makes it easy to curl shorter, layered hair without getting loose.
Hair Curlers And Curling Tongs,best curling wand for short hair,Dry Hair Curling Tongs,Temperature Control Curling Irons,Hair Curling Wands & Curling Tongs
Ningbo Meirou Electric Appliance Co.,Ltd. , https://www.mrhairdryer.com